First cycle adive

[md1]

My white blood cells are low, not sure if that's common for someone who trains a lot, or I'm fighting an infection or just low

 

[md1]

These are normal results for someone who trains a lot (training impact shbg,free T, oestradiol)

How does this look to be running 500mg a week or should a lower does be beneficial

 

[Fredqld]

How does this look to be running 500mg a week or should a lower does be beneficial

Projected Hormonal Profile Changes: 16 Weeks of Supraphysiological Testosterone (500mg/week)​

Comparative ****ysis of Hormonal Parameters​

Hormone	Current Value	Projected Value (16 weeks)	Reference Range	Magnitude of Change	Physiological Significance
Total Testosterone	26 nmol/L	70-150 nmol/L	10.0-33.0 nmol/L	↑↑↑ 3-6× increase	Supraphysiological androgen exposure; greatly exceeds normal physiological range
Free Testosterone (calc)	347 pmol/L	1500-3000 pmol/L	150-700 pmol/L	↑↑↑ 4-9× increase	Dramatic elevation in bioavailable testosterone; drives anabolic effects in target tissues
Luteinizing Hormone (LH)	7 IU/L	<0.5 IU/L	1-10 IU/L	↓↓↓ >90% decrease	Complete HPG axis suppression due to negative feedback on hypothalamus and pituitary
Follicle Stimulating Hormone (FSH)	5 IU/L	<0.5 IU/L	1-10 IU/L	↓↓↓ >90% decrease	Suppression of spermatogenesis; potential long-term fertility implications
Oestradiol	145 pmol/L	250-400+ pmol/L	<150 pmol/L	↑↑ 70-175% increase	Elevated due to increased aromatization of excess testosterone; potential gynecomastia risk
*** Hormone Binding Globulin	64 nmol/L	15-25 nmol/L	13-71 nmol/L	↓↓ 60-75% decrease	Androgen-mediated suppression of hepatic SHBG production
Prolactin	160 mIU/L	120-180 mIU/L	<300 mIU/L	↔ Minimal change	Generally not directly affected by testosterone administration
Progesterone	2 nmol/L	1-2 nmol/L	<3 nmol/L	↔ Minimal change	Minimal direct effect of exogenous testosterone on progesterone levels

Additional Parameters Not in Original Panel​

Parameter	Expected Change	Physiological Significance
Hematocrit	↑↑ Significant increase	Increased erythropoiesis; potential polycythemia risk
Hemoglobin	↑↑ Significant increase	Increased oxygen-carrying capacity; potential cardiovascular strain
HDL Cholesterol	↓↓ Significant decrease	Adverse lipid profile changes; increased cardiovascular risk
LDL Cholesterol	↑ Moderate increase	Altered hepatic lipid metabolism
ALT/AST (Liver enzymes)	↑ Mild-moderate increase	Potential hepatic stress from metabolizing exogenous androgens
Sperm Count	↓↓↓ Severe decrease	Suppressed spermatogenesis; temporary infertility
Insulin Sensitivity	↑↓ Variable effects	Complex interaction with glucose metabolism; potential initial improvement followed by possible deterioration

Recovery Timeline Post-Cessation​

Duration of suppression after discontinuation varies significantly between individuals. Approximate expectations:

Parameter	Recovery Timeframe	Factors Affecting Recovery
HPG Axis Function (LH/FSH)	4 weeks - 12+ months	Duration of use, individual genetics, post-cycle therapy protocol
Spermatogenesis	3-12+ months	Age, prior fertility status, duration of suppression
SHBG	2-8 weeks	Baseline levels, body composition, metabolic health
Hematological Parameters	4-16 weeks	Baseline values, hydration status, other medications

Clinical Implications​

The projected hormonal alterations represent a significant deviation from physiological homeostasis with multiple potential health implications:

1. Reproductive System: Profound suppression of the HPG axis with risk of prolonged hypogonadism after cessation
2. Cardiovascular System: Altered lipid profile, increased hematocrit, and potential blood pressure effects
3. Psychological Effects: Potential mood alterations, including aggression or emotional lability
4. Metabolic Effects: Changes in body composition, insulin sensitivity, and hepatic function
5. Cosmetic Effects: Potential for accelerated male pattern baldness, acne, and gynecomastia

Methodological Considerations​

These projections represent averages based on research literature. Individual responses may vary significantly due to:

• Genetic polymorphisms affecting androgen metabolism
• Age-related differences in hormonal responsiveness
• Concurrent medications or supplements
• Body composition and metabolic health
• Psychological and environmental factors
• Compliance with administration protocol
• Quality and purity of administered testosterone

---

Note: This ****ysis is provided for academic purposes only and should not be interpreted as medical advice or endorsement of supraphysiological testosterone use. Such usage carries significant health risks and legal implications in many jurisdictions.

 

[Fredqld]

How does this look to be running 500mg a week or should a lower does be beneficial

here for 150mg, but going on gear is probably a pretty bad idea at your age and fitness level,

Projected Hormonal Profile Changes: 16 Weeks of Testosterone (150mg/week)​

31-Year-Old Athletic Male with 10% Body Fat​

Comparative ****ysis of Hormonal Parameters​

Hormone	Current Value	Projected Value (150mg/week)	Reference Range	Magnitude of Change	Physiological Significance
Total Testosterone	26 nmol/L	35-55 nmol/L	10.0-33.0 nmol/L	↑ 1.3-2.1× increase	Mild-moderate supraphysiological elevation; just above or near upper physiological limit
Free Testosterone (calc)	347 pmol/L	700-1000 pmol/L	150-700 pmol/L	↑ 2-2.9× increase	Modestly elevated bioavailable testosterone; sufficient for anabolic effects with reduced side effect risk
Luteinizing Hormone (LH)	7 IU/L	0.8-2.0 IU/L	1-10 IU/L	↓↓ 70-89% decrease	Significant but potentially partial HPG axis suppression
Follicle Stimulating Hormone (FSH)	5 IU/L	1.0-2.0 IU/L	1-10 IU/L	↓↓ 60-80% decrease	Moderate suppression of spermatogenesis; more favorable for recovery
Oestradiol	145 pmol/L	160-220 pmol/L	<150 pmol/L	↑ 10-50% increase	Modest elevation from baseline; lower risk profile for estrogen-related effects
*** Hormone Binding Globulin	64 nmol/L	35-45 nmol/L	13-71 nmol/L	↓ 30-45% decrease	Moderate suppression while remaining within physiological range
Prolactin	160 mIU/L	155-165 mIU/L	<300 mIU/L	↔ Minimal change	Negligible impact at this dosage
Progesterone	2 nmol/L	1.8-2.0 nmol/L	<3 nmol/L	↔ Minimal change	Negligible direct impact from exogenous testosterone

Dose Comparison ****ysis​

Parameter	150mg/week	200mg/week	500mg/week	Clinical Significance of 150mg Dose
Total Testosterone	35-55 nmol/L	45-70 nmol/L	70-150 nmol/L	Closer to physiological range; less dramatic hormonal disruption
HPG Axis Suppression	Partial to significant	Significant	Complete	Potentially preserves some endogenous production
Estrogen Conversion	Modest elevation	Moderate elevation	Substantial elevation	Significantly reduced gynecomastia risk
Hematological Effects	Mild increase (1-3%)	Moderate increase (2-4%)	Significant increase (4-8%)	Substantially lower polycythemia risk
Lipid Profile Changes	Minimal to mild	Moderate	Significant	Less impact on cardiovascular risk markers
Recovery Time Frame	1-4 months	2-6 months	4-12+ months	More favorable recovery profile

Additional Parameters Not in Original Panel​

Parameter	Expected Change (150mg/week)	Physiological Significance
Hematocrit	↑ Mild increase (1-3%)	Modest stimulation of erythropoiesis; low polycythemia risk
Hemoglobin	↑ Mild increase (0.3-1.0 g/dL)	Slight increase in oxygen-carrying capacity
HDL Cholesterol	↓ Mild decrease (5-15%)	Modest impact on cardioprotective lipoproteins
LDL Cholesterol	↑ Minimal increase (0-10%)	Minor disruption of lipid metabolism
ALT/AST (Liver enzymes)	↑ Minimal change	Minimal hepatic stress at this dosage
Sperm Count	↓ Moderate decrease	Partial suppression of spermatogenesis with favorable recovery profile
Insulin Sensitivity	↑ Mild improvement	Positive metabolic effects without significant complications

Recovery Timeline for 150mg/week Protocol​

Parameter	Estimated Recovery Time	Factors Affecting Recovery
HPG Axis Function (LH/FSH)	1-4 months	Less profound suppression allows more rapid recovery
Spermatogenesis	2-6 months	Better preservation of testicular function
SHBG	2-4 weeks	Milder suppression with prompt normalization
Hematological Parameters	2-8 weeks	Minimal elevation allows quicker return to baseline

Specific Considerations for Athletic Individual with Low Body Fat​

1. Performance Implications:
   • Enhanced recovery between intense training sessions
   • Modest improvements in strength and power output
   • Potential for slight lean mass increase even in already athletic individual
   • Lower risk of performance disruption from side effects
2. Hormonal Equilibrium:
   • For an individual with 10% body fat:
     • Less dramatic aromatization due to lower adipose tissue
     • Potentially more favorable testosterone:estrogen ratio
     • Lower likelihood of requiring estrogen management strategies
3. Therapeutic vs. Enhancement Threshold:
   • 150mg/week represents a dose that falls near the upper boundary between:
     • High-normal therapeutic replacement
     • Low-end performance enhancement
   • May provide subjective well-being benefits with modest performance enhancement
4. Regulatory Considerations:
   • Within prescribable range for testosterone replacement therapy (TRT)
   • May produce therapeutic testosterone levels in some individuals
   • Typically requires medical supervision and monitoring

Methodological Limitations​

These projections are educated estimates based on research literature and clinical observations. Individual responses may vary significantly due to:

• Genetic factors affecting testosterone metabolism
• Individual variations in hypothalamic-pituitary sensitivity
• Testosterone ester pharmacokinetics (not specified in query)
• Administration frequency and resulting hormonal stability
• Individual aromatase activity levels
• Concurrent nutritional and training variables

---

Note: This ****ysis is provided strictly for academic purposes and should not be interpreted as medical advice or endorsement of testosterone use outside therapeutic contexts. Even at lower doses, exogenous testosterone administration should occur only under appropriate medical supervision.

 

[md1]

here for 150mg, but going on gear is probably a pretty bad idea at your age and fitness level,

I'll deep into it and give it a read! Cheers which site did you collect this info from??

In your opinion what's the concerning cons for me, that you think I should consider??

 

[Fredqld]

I'll deep into it and give it a read! Cheers which site did you collect this info from??

In your opinion what's the concerning cons for me, that you think I should consider??

Claude (I tested with my blood tests, and the projections were extremely accurate at the lower bound.)

LH and FSH levels often do not fully rebound, leading to low testosterone and fertility issues. I believe that anabolic steroids can be beneficial after having children, especially for individuals over 45 or 50, when maintaining or building muscle and stamina becomes challenging.

 

[flexymcflexface]

Just got my bloods done
They are all across 10 pages but here's my test levelsView attachment 3216

Put up all 10 mate tells us lots more.

Test is fine not crazy high but your not low

 

[md1]

Put up all 10 mate tells us lots more.

Test is fine not crazy high but your not low

 

[Fredqld]

Please Remove the one with your name

 

[Fredqld]

High oestradiol, with this low %BF, could create anxiety issues, like your white cells; this could be related to high-intensity training. Congratulations for being that motivated

 

[md1]

Please Remove the one with your name

Good pick up, thank. dont know how to exactly hahah

 

[md1]

High oestradiol, with this low %BF, could create anxiety issues, like your white cells; this could be related to high-intensity training. Congratulations for being that motivated

Should I be trying to lower the high oestradiol? My research has suggested my current diet should be good to keep it lower and balanced