Like to hear from guys just on test e and retatrutide,dosage and effects, hopefully good results
- Thread starter Shane
- Start date
I'm just waiting delivery on mine, AusPost messed up and it's been doing a tour of Australia.
Only planning to lose 2kg for holiday and then will start my bulk once I'm back. I don't want to start bulking from 12-13%. Then will use again at end of bulk.
I was planning to titrate in 3 week steps, 0.5mg, 1.5mg, 3mg, 4mg.
From the trials, people tolerated 3mg almost as well as 1.5mg once past the initial adaptation, most of the nausea was between weeks 1-2, after that gut adapation, and the jump from 1.5-3 in trial didn't increase drop out rate.
BUT this is all based on the trials, guess I'll find out how I respond in a few weeks.
Only planning to lose 2kg for holiday and then will start my bulk once I'm back. I don't want to start bulking from 12-13%. Then will use again at end of bulk.
I was planning to titrate in 3 week steps, 0.5mg, 1.5mg, 3mg, 4mg.
From the trials, people tolerated 3mg almost as well as 1.5mg once past the initial adaptation, most of the nausea was between weeks 1-2, after that gut adapation, and the jump from 1.5-3 in trial didn't increase drop out rate.
BUT this is all based on the trials, guess I'll find out how I respond in a few weeks.
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Just keep in mind the studies don’t guarantee your gut will handle each step cleanly. Best to monitor your tolerance. If you hit 1.5mg and feel good, move to 3mg. If you don’t, hold the dose longer.
I seen your photos brother, you're already pretty lean. This should shred you right up.
Yeah totally, I'm just relying on the law of averages, really hoping I'm able to tolerate it.
Thanks. Looking forward to seeing the results, don't think I've been below 12% for 20 years.
Reta is pretty much magic, and I am going to keep it at low dose as anti aging/anti inflammatory (it shrinks cholesterol levels/visceral fat/fatty liver/increases metabolism, basically makes you healthier)
Well just did my first Reta dose at 0.5mg, well no idea what I actually injected, it was made worse by the fact that I have 60mg in 3ml, could put 4ml of bac in, but calculations easier with 3ml. I had to inject 2.5 units. A 10ml vial would have been so much easier.
I'm glad I'm not the only one that struggles with with maths of all this stuff.
I was trying to work out yesterday how much I want to try and buy for a short cycle.
What I had failed to plan for is the fact that I'd have to titrate up, my vial means it'll be needing to be used far beyond it's expected shelf live. Reta decays after about 30 days, but I can't find documentation on decay rate.
From Chat GPT
For retatrutide reconstituted in bacteriostatic water and stored refrigerated (2–8 °C), the commonly assumed practical decay rate is:
This is not from published stability studies — it is inferred from:
Most experienced labs and compounders treat it as:
This assumes:
For retatrutide reconstituted in bacteriostatic water and stored refrigerated (2–8 °C), the commonly assumed practical decay rate is:
Estimated potency loss
- ~5–10% per month
This is not from published stability studies — it is inferred from:
- peptide size and structure (long, complex peptide)
- behaviour of similar long GLP-1–based peptides
- compounding pharmacy handling assumptions
Practical stability window
Most experienced labs and compounders treat it as:
- Best use: within 30–45 days
- Acceptable use: up to 60 days with some potency loss
- Beyond 60–90 days: degradation becomes more likely to be clinically noticeable, even if not obvious visually
This assumes:
- true refrigeration (not door storage)
- minimal vial punctures
- no shaking
- protection from light
Why retatrutide is not on the “stable” end
- Long peptide chain
- Multiple receptor activity correlates with structural complexity
- Similar GLP-1 class peptides show measurable degradation after reconstitution even under ideal storage
Based on pharmacokinetic theory it’s preferable to do a single weekly injection vs split dose. Higher average and larger peak is thought to lead to better receptor activation. But also may cause increase sides. This is theory though and hasn’t been studied for Reta. But this is why some other drugs are weekly dosed.
What dosage you on and how often do you take it
